L12 Short history of DNA

Cdcgovphilimages200301105phil2842loresjpg

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: th http://phil.cdc.gov/phil_images/20030110/5/PHIL_2842_lores.jpg encarta.msn.com Streptococcus pneumoniae www.medicalook.com 6 7 Early evidence of genetic material “the transforming principle” 1928 - Frederick Griffith Conclusion: Living R bacteria had been transformed into pathogenic S bacteria by an unknown, heritable substance from dead S cells 8 Oswald Avery Colin MacLeod Maclyn McCarty 1. Heat killed S cells 2. Extracted carbohydrate, DNA and protein separately 3. Added extracts to R cells 4. Injected into mice 5. Which extract killed mice? 9 DNA as genetic material "If we are right, and of course that is not yet proven, then it means that nucleic acids are... functionally active substances in determining the [..] activities and [..] characteristics of cells … [Thus] it is possible to induce predictable and hereditary changes in cells. This is something that has long been the dreams of geneticists." --Oswald T. Avery, 1943 10 Is DNA or protein the genetic material? 1952 Alfred Hershey and Martha Chase “the blender e...
View Full Document

This note was uploaded on 03/29/2009 for the course BIO 325 taught by Professor Saxena during the Fall '08 term at University of Texas at Austin.

Ask a homework question - tutors are online