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L8 Inheritance patterns pt2

L8 Inheritance patterns pt2 -...

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Inheritance Patterns Pt 2 Multiple genes http://homepage.usask.ca/~schmutz/Macintosh.jpg 1
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Last Time Molecular basis of single gene phenotypes Dominance can be expressed in as a range, not an absolute Why are dominant disease alleles still around??? Environmental influences Genes with multiple alleles Traits influenced by sex Pleiotropy 2
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Multiple gene inheritance patterns Overview of gene interaction Epistasis - the masking effect Complementation - two genes, one phenotype Modifying genes - tweaking phenotypes Gene redundancy - the backup plan 3
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Polygenic inheritance (‘many genes’) Many genes contribute to a single phenotype Example: skin color or height Gene 1 Gene 2 Gene 3 Phenotype WWW.FRANKLINCO.K12.NC.US 4
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Overview of gene interactions Genes can mask, tweak, complement, and suppress the phenotypes of other genes. Be aware of the expected patterns of inheritance in each case. Try to imagine what’s going on at the molecular level (protein - protein interaction, enzymes in a given pathway) Make a hypothesis and draw out a Punnett square of the expected results - do the data fit?
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