Chem 114A 2009 LEC 9 AS GIVEN 0203090

Chem 114A 2009 LEC 9 AS GIVEN 0203090 - Chem 114A Amino...

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Chem 114A Amino acids, peptides, and proteins Lecture 9 February 2, 2009 (Tuesday) 1
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Protein is essential for nutrition. 2
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Protein. Polymer of amino acids. Amino acid (monomer). Peptide (small polymer with 2-20 amino acids.) Protein (long polymer with 50 – 500 amino acids). Twenty different amino acids in proteins. Linear polymer. Folds into complex shape. 3
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Myoglobin contains 153 amino acids arranged in specific order. MGLSDGEWQL VLNVWGKVEA DIPGHGQEVL IRLFKGHPET LEKFDKFKHL KSEDEMKASE DLKKHGATVL TALGGILKKK GHHEAEIKPL AQSHATKHKI PVKYLEFISE CIIQVLQSKH PGDFGADAQG AMNKALELFR KDMASNYKEL GFEG 4
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The linear polymer of amino acids folds into a specific three-dimensional structure to form functional Myoblobin. 5
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adds functionality to that provided by the amino acid sidechains. Myoglobin has a prosthetic group to provide functionality. 6
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Chem 114A 2009 LEC 9 AS GIVEN 0203090 - Chem 114A Amino...

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