Acyl%20Substitution

Acyl%20Substitution - Nucleophilic Substitution at an Acyl...

Info iconThis preview shows pages 1–5. Sign up to view the full content.

View Full Document Right Arrow Icon
Nucleophilic Substitution at an Acyl Carbon: The Addition-Elimination Mechanism H 3 CC l O H 3 CO O O CH 3 H 3 O CH 3 Increasing Chemical Reactivty H 3 CN O CH 3 CH 3 See on-line handout entitled “Introduction to Acyl Derivatives” to better understand these trends in Reactivity
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Nucleophilic Substitution at an Acyl Carbon: The Addition-Elimination Mechanism General Mechanism Specific Case: Anhydride Formation
Background image of page 2
Acid Chloride Formation H 3 CO C H 3 O H 3 C H 3 O Addition Elimination Tetrahedral Intermediate H 3 O H O O H CH 3 O H H 3 O CH 3 HO Saponification (basic hydrolysis of an ester) Reaction of Acid Chlorides with Alcohols Nucleophilic Substitution at an Acyl Carbon: The Addition-Elimination Mechanism H 3 H O
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Background image of page 5
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 5

Acyl%20Substitution - Nucleophilic Substitution at an Acyl...

This preview shows document pages 1 - 5. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online