Reduction of Acyl DerivativesReaction of an Ester with LiAlH4 : An Addition-Elimination-AdditionReaction of an Amide with LiAlH4 : An Addition-Elimination-Addition…with a twistH3COCH3OH3CH3OAdditionEliminationTetrahedralIntermediateH3CHOHOCH3H3OHHOHOHH3OHHAdditionHAlHHHAlH3HHAlH3Leaving groupNitrogen is a much worse leaving group than oxygen, which is why the mechanism for amide
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This note was uploaded on 03/31/2009 for the course CH 318M taught by Professor Bocknack during the Spring '08 term at University of Texas.