BIPN100practiceproblems - Additional Practice Problems 1...

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Additional Practice Problems 1). What is the difference between temporal and spatial summation? Which is likely to come into play at neurons in the cortex (the outermost or superficial layer of an organ, and especially in the brain). Why? 2). What would be the consequences at both the molecular and behavioral level of blocking acetylcholinesterase (AChase) in the brain? Why? . 3). How does the response generated by ionotropic receptors differ from the response generated by metabotropic receptors? 5). In the mammalian brain, glutamate acts on ligand-gated ion channels to produce rapid excitatory PSPs. a). What ions flow, and why are they PSPs excitatory? b). You have found a strange animal in which stimulating the glutamatergic nerve terminal to release glutamate elicits a rapid hyperpolarization in the postsynaptic neuron. Name a mechanisms that might account for this. c). What might be the mechanism if the hyperpolarization had been slow (time course of seconds)? 6). What are gap junctions? 7). You are investigating the role of the Na/K ATPase in establishing the resting membrane potential of a squid giant axon. You apply the pump blocker ouabain and measure the resting membrane potential before and after blocking pump activity. a). Calculate the resting membrane potential, considering only the contribution of K+ before addition of the drug. The original K+ concentrations are: 90 mM internal and 4 mM external. b).
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BIPN100practiceproblems - Additional Practice Problems 1...

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