L11- Spinal Chord Injury

L11- Spinal Chord Injury - Useful websites

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon
http://www.acorda.com/pipeline_fampridine_sci1.asp http://www.christopherreeve.org/site/c.geIMLPOpGjF/b.899265/k.CC03/Home.htm http://www.fscip.org/ http://www.campaignforcure.org/ http://www.miamiproject.miami.edu/x933.xml http://www.ninds.nih.gov/funding/areas/repair_and_plasticity/fore_sci.htm http://www.ninds.nih.gov/news_and_events/proceedings/sci_translation_workshop.htm http://www.proneuron.com/ClinicalStudies/index.html http://www.reeve.uci.edu/forsci/replication.php http://www.seikagaku.co.jp/ir/pdf/ar05.pdf Useful websites
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
1. Review 1. Descending motor pathways, central pattern generator and plasticity 2. Molecular and Cell therapies
Background image of page 2
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Other cells: microglia macrophage T-cells fibroblasts Some of these cells are initially beneficial for the spinal cord, either preventing secondary injury/degeneration or promoting regeneration, but they over times become obstacles for regeneration; Understanding the underlying mechanisms may allow strategies to turn them into beneficial forces Understanding cellular environments during development, at mature stage and after injury
Background image of page 6
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 8
1. Review 1. Descending motor pathways, central pattern generator and plasticity 1. Molecular and cell therapies
Background image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 10
Background image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
E. Measures of spinal cord injury outcome Basso, Beatie and Bresnahan (BBB) locomotor rating scale 0-21score (with a score of 0 assigned for no observable hindlimb movement and 21 for normal locomotion) Basso Mouse Scale (BMS) 0-9 (with a score of 0 assigned for no ankle movement and 9 for frequent plantar stepping, paws parallel at initial contact and lift off, normal trunk stability and tail always up) Other tests : Rope climbing, swimming, adhesive tape removal, analysis of footprints and gait.
Background image of page 12
Image of page 13
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/01/2009 for the course BIPN 150 taught by Professor Fortes during the Winter '09 term at UCSD.

Page1 / 42

L11- Spinal Chord Injury - Useful websites

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online