L07.Anxiety

L07.Anxiety - 1/27 1/29 2/3 2/5 2/10 2/12 StressandAnxiety...

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1/27 Stress and Anxiety (Kuo-Fen Lee) 1/29 Alzheimer’s Disease Part I (Eddie Koo) 2/3 Alzheimer’s Disease Part I (Kuo-Fen Lee) 2/5 Spinal Cord Injury Part I (Binhai Zheng) 2/10 Mid-term exam 2/12 Spinal Cord Injury Part II (Kuo-Fen Lee)
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Stress and Anxiety Kuo-Fen Lee The Salk Institute Jan. 27, 2009
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Fight or Flight Anxiety and Anger Stress/Anxiety Response Stress and anxiety are adaptive behaviors against life-threatening situations.
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Genes Environments Behavior Circuits Immune System Endocrine System Brain Neural System
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Approaches to understand stress and anxiety Human/Monkey/Rodent 1. Behavioral modeling 1. Anatomy 3. Circuitry 4. Genetics 5. Cellular mechanisms 6. Molecular mechanisms Levels of resolution The ultimate goal is to develop interventional strategies e.g. lesion, functional imaging e.g. retrograde labeling electrophysiology e.g. twin study, linkage analysis polymorphisms
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1. Anatomic correlates and neural circuitry of stress and anxiety 2. Physiological responses of stress and anxiety 3. Neurotransmitters and neuropeptides in stress and anxiety (therapeutic targets) 4. The developmental origins of anxiety
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1. Elevated plus maze 3. Open field
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This note was uploaded on 04/01/2009 for the course BIPN 150 taught by Professor Fortes during the Winter '09 term at UCSD.

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L07.Anxiety - 1/27 1/29 2/3 2/5 2/10 2/12 StressandAnxiety...

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