L01 - rain tumors Gray matter - cell bodies White matter -...

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BIPN 150: Diseases of the Nervous System Lecture 1 Reading: a. Neuroscience (4th ed) pg 815-857 b. Watch Kandel Lecture 1: Mapping memory in the brain URL:http://www.hhmi.org/biointeractive/lectures/
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Major types of disorders include: 1. N eurogenetic diseases, eg. Huntington disease and muscular dystrophy 2. D evelopmental disorders, eg. cerebral palsy 3. D egenerative diseases of adult life, eg. Parkinson disease and Alzheimer disease 4. M etabolic diseases, eg. Gaucher disease 5. C erebrovascular diseases, eg. stroke and vascular dementia, Kawasaki syndrome 6. T rauma, eg. spinal cord and head injury 7. C onvulsive disorders, eg. Epilepsy 8. I nfectious diseases, eg. AIDS dementia 9. B
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Unformatted text preview: rain tumors Gray matter - cell bodies White matter - myelinated axon tracts White matter on outside of spinal cord Cortex: 6 layers cytoarchitecture defined by Brodmann in 1909 Lesion of 1 side of parietal cortex: contralateral neglect syndrome Blood supply to brain: Strokes 50% thrombic - atherosclerotic plaque 30% embolic - blood clot, treat with tissue plasminogen activator (TPA) 20% hemorrhagic - blood vessel rupture, treat with surgery Blood brain barrier - an obstacle to drugs Phineas Gage - trauma Oliver Sacks: Awakenings - documents an encephalitis epidemic in NYC in the 1920s that caused catatonia/dystonia. QuickTime and a decompressor are needed to see this picture....
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This note was uploaded on 04/01/2009 for the course BIPN 150 taught by Professor Fortes during the Winter '09 term at UCSD.

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L01 - rain tumors Gray matter - cell bodies White matter -...

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