mt%20inh - CYTOPLASMIC INHERIT ANC E Mitochondria and...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
CYTOPLASMIC INHERITANCE Mitochondria and Chloroplasts contain DNA • Human mtDNA is 16,569 base pairs in a closed circle; plant and fungal mtDNAs are usually larger. To see a map of human mt DNA go to: http://www.gen.emory.edu/MITOMAP/report.html • Typical ctDNA is > 121,000 base pairs in a circle. These organelles generally pass from one generation to the next only via the egg, not sperm or pollen. All progeny inherit the organelle DNA sequence of their mother! The DNA in the organelles codes for: • rRNAs for translation inside the organelle • tRNAs for translation inside the organelle • mRNAs for some subunits of proteins that are made in and function inside the organelle - proteins coded include: ct/mt ribosomal proteins and an RNA polymerase cytochrome oxidases, ATPases, and electron transport complex component in mtDNA photosystem, cytochromes and electron transport complex proteins in ctDNA Note that other protein subunits for many of the same complexes are coded for by nuclear genes, transcribed in the nucleus, translated in the cytoplasm, and transported into the organelle with the aid of "signal sequences" built into the beginning of the chain of amino acids.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Inheritance of defects in the organelle genes is strictly maternal. The best test for maternal inheritance is to make reciprocal crosses. Progeny of an affected female will all show the trait, but if an
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/29/2008 for the course GENE 310 taught by Professor Magill during the Spring '08 term at Texas A&M.

Page1 / 4

mt%20inh - CYTOPLASMIC INHERIT ANC E Mitochondria and...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online