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Unformatted text preview: Chapter 4 Chapter 4 Myoglobin and Myoglobin and Hemoglobin: Hemoglobin: A Study of Protein A Study of Protein Structure and Function Structure and Function Chapter 4 Myoglobin and Hemoglobin: A Study of Protein Structure and Function 1. Understand the chemical characteristics of the R groups that distinguish the 20 amino acids. 2. Understand how a protein’s amino acid sequence is determined. 3. Understand the four levels of protein structure. 4. Understand the constraints on polypeptide conformation. 1. Understand the structural characteristics of the α helix and the β sheet and how these differ from irregular secondary structure. 6. Understand that proteins have a hydrophilic surface and a hydrophobic core. 7. Understand the forces that stabilize proteins and guide protein folding. 8. Understand how O 2 binds to myoglobin. 9. Understand the advantages of quaternary structure. 10. Understand how hemoglobin is related to myoglobin in structure, function and evolution. 11. Understand how O 2 cooperatively binds to hemoglobin. 12. Understand how the Bohr effect and BPG modulate hemoglobin function in vivo....
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- Spring '07
- Chemistry, Myoglobin Hemoglobin