protein3pp - Proteins Substrates? Digestion Stomach HCL...

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1 Proteins Substrates?? Digestion •S tomach – HCL – Pepsin pepsinogen pepsin H C l p p s in Bonds worked on: Most aa trypsinogen e n te p tid e chymotrypsinogen procarboxypeptidases chymotrypsin carboxypeptidase A carboxypeptidase B aminopeptidases in Bonds worked on: aromatic aa met, asn, his C-terminal neutrals C-terminal dibasics N-terminals Dibasic aa •Small Intestine
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2 Absorption Same as ASC no asc Ala, Cys, Ser, other 3-4 C yes ASC Ala, other short chains yes A Phe, Met yes PHE dibasics no y proline yes Imino Thr, Ala, neutrals yes B Leucine and other neutrals no L Examples Sodium Carrier Absorption • About 1/3 as individual amino acids • About 2/3 as very short peptides – 2 or 3 amino acids • Portal system to the liver • Liver decides fate based on priorities and needs
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3 EAA • 9 essentials – Tryptophan –Va l ine – Threonine – Isoleucine – Leucine –Lys ine – Phenylalanine – Methionine – Histidine Nitrogen status
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protein3pp - Proteins Substrates? Digestion Stomach HCL...

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