Lecture 22- Membrane Biology

Lecture 22- Membrane Biology - Lecture 22- Membrane Biology...

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Lecture 22- Membrane Biology -Carbohydrates for cell-to-cell contact -Lipid bilayer Hydrophilic head Hydrophobic fatty acid tail -The lipid bilayer is called “Amphipathic” because it has polar and non polar regions in one molecule (eg, detergents) Fatty Acid Structure - Saturated fatty acid - No carbon-carbon double bonds - In a membrane, will not transport molecules very well, less fluidity - Unsaturated fatty acid - At least one carbon-carbon double bond; fewer Hydrogens - Trans unsaturated: Hydrogens in kink across from each other (on the diagonal); kink not as severe
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- Cis unsaturated: both Hydrogens in kink are on the same side; bigger kink than trans - Saturation affects membrane fluidity. An unsaturated fatty acid has more fluidity than a saturated fatty acid because there is more space between the hydrophobic fatty acid tails, and thus more room for a protein or molecule to travel through the membrane. Unsaturated Saturated -A double bond creates a kink in the fatty acid tail, which creates space within the membrane. - Saturated fatty acids are solid at room temperature; unsaturated fatty acids are liquid at room temperature Trans Fatty Acids - Very rare in nature; partial hydrogenation produces trans fats
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- There are health concerns associated with trans fats: they have a unique-altered metabolism, a different membrane structure. Our bodies are not used to this molecule, and thus we do not know how to handle it - Partial hydrogenation is the process whereby unsaturated fatty acids are converted to saturated
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This note was uploaded on 04/04/2009 for the course BIOLOGY 1222 taught by Professor Haffie during the Spring '09 term at UWO.

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Lecture 22- Membrane Biology - Lecture 22- Membrane Biology...

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