Lecture 32-Viral Genetics

Lecture 32-Viral Genetics - Lecture 32 Viral...

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Lecture 32- Viral Genetics -Generalized transduction: where any gene is equally likely to be transferred; random -Sometimes a piece of the host chromosome persists after the virus DNA takes over the cell, and the bacterial DNA is stuffed into the baby virus’s head (not viral DNA) and so when the virus invades a cell it injects bacterial DNA, i.e., sexually recombining with the bacterial cell, (it is no longer infectious, but still tries to invade the bacteria cell) -The donor dies after the baby viruses escape from the cell -Specialized transduction: Only will occur with specific genes, just those on their side of the insertion point can be moved; not random -When the viral DNA is injected into the host chromosome it circularises and integrates DNA into the host chromosome, where it gets replicated “for free” in the bacterial cell -After the cell divides, the two circles that have combined separate -As the virus is leaving, by mistake a piece of the wrong DNA may be taken and a piece left behind and some of the bacterial DNA may be packaged into the virus (e.g. Gal+ gene allows the cell to use
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