Lecture 001 - Antibiotic Resistance

Lecture 001 - Antibiotic Resistance - 1 Bio1222 Lecture 2:...

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Unformatted text preview: 1 Bio1222 Lecture 2: Antibiotic Resistance Bio1222 So what is an antibiotic? 2 Bio1222 Antibiotics: True wonder drugs Staph infection Staphylococcus aureus Tuberculosis Mycobacterium tuberculosis Pneumonia Streptococcus pyogenes Syphilis Treponema pallidum Bio1222 One bacterium, two bacteria 3 Bio1222 Antibiotics: Modes of action Bio1222 Antibiotic resistance 4 Bio1222 60 60 40 40 20 20 1 9 8 2 1 9 8 2 1 9 8 6 1 9 8 6 1 9 9 1 9 9 1 9 9 4 1 9 9 4 1 9 9 8 1 9 9 8 2 2 2 2 Methicillin resistance Vancomycin resistance The rise in antibiotic resistance Bio1222 Mechanisms of resistance 5 Bio1222 Antibiotic Resistance is Genetic Antibiotic resistance may result from the action of proteins (e.g.enzymes) that are, in turn, coded by genes Bio1222 July 2006 Antibiotic Resistance is Mobile 6 Bio1222 Antibiotic Resistance is Mobile Entire genome of drug resistant C. difFcile 11% of the sequence is mobile! (inner red circle) Bio1222 Resistance Genes are Mobile...
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This note was uploaded on 04/04/2009 for the course BIOLOGY 1222 taught by Professor Haffie during the Spring '09 term at UWO.

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Lecture 001 - Antibiotic Resistance - 1 Bio1222 Lecture 2:...

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