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Lecture 020 - Genetic Variation

Lecture 020 - Genetic Variation - Lecture outline genetic...

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1 Bio1222 Lecture outline: genetic variation Lecture outline: genetic variation What is it and why does it matter? Selection: does it always reduce genetic variation? Other evolutionary mechanisms: – Mutation – Migration Genetic drift Nonrandom mating Bio1222 Genetic variation Individual level Proportion of heterozygous loci Population level Proportion of polymorphic loci Alleles per locus Average heterozygosity
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2 Bio1222 Why does it matter? Why does it matter? Bio1222 Why is there (usually) so much? Why is there (usually) so much? Classical model of variation Any allele is either helpful or harmful selection should eventually replace bad with good alleles So, genetic variation should be rare and temporary But, most natural populations contain lots of GV… ???
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