Lecture 9 Mood Disorders II

Lecture 9 Mood Disorders II - Part 2 1st Generation MAO...

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Part 2
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1st Generation MAO Inhibitors i.e. Parnate Side effects: Dry mouth, dizziness, nausea, headaches, interactions with particular foods and other medications. High blood pressure is a very serious problem with these medications.
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2nd Generation Tricylcic antidepressants i.e. Tofranil (Imipramine), Elavil (Amitriptyline) Side effects: Cardiovascular problems, blurred vision, anxiety, irritability, fatigue, dry mouth, constipation, gastric disorders, weight gain. Very dangerous when taken in overdose. Can trigger manic episodes.
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3rd Generation Selective Serotonin Reuptake Inhibitors (SSRI’s) i.e. Prozac, Zoloft, Paxil Side effects: Nervousness, fatigue, gastrointestinal problems, dizziness, headaches, insomnia, sexual dysfunction. Can trigger manic episodes. Generally less dangerous than the Tricyclics and MAO-inhibitors.
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Lithium Carbonate : Very toxic in high levels. Therapeutic effect is not well understood.
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Anti-Convulsant medications : Tegretol is one common example. Generally, less effective than Lithium.
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Anti-psychotic medications : Used when patient becomes psychotic. Also known as “major tranquilizers.”
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Lecture 9 Mood Disorders II - Part 2 1st Generation MAO...

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