bicd130_06_lecture1r - BICD 130 Embryos Genes and...

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Unformatted text preview: BICD 130 Embryos, Genes, and Development BICD 130 TAs' Office Hours Joe Fontana: Derek Lemons: Mon 4:00-5:00 PM 4146 Bonner Hall Tue 10:30-11:30 AM 4146 Bonner Hall BICD 130 Current Section Schedule Section Day Time Room 1 2 3 4 W W F F 4:00p - 4:50p 5:00p - 5:50p 8:00a - 8:50a 9:00a - 9:50a CENTR 218 CENTR 218 WLH 2208 WLH 2208 Fertilization The process by which two gametes (reproductive cells) fuse to create, and initiate the development of, a new individual with a genome derived from both parents Egg (ovum) is haploid Oocyte while still completing meiosis before fertilization Contents of the egg Haploid nucleus Nutrient proteins (yolk) Protein synthesis machinery, including ribosomes and tRNA Messenger RNAs (dormant) Morphogenetic factors (proteins, mRNAs) -- determinants of embryonic cell fate Structure of the sea urchin egg Structure of the mammalian egg Cumulus Ovum Zona pellucida Structure of mature mammalian sperm DAPI (DNA) Mitochondria Tubulin Stage of egg maturation at the time of sperm entry Stage of egg maturation at the time of sperm entry Four major components of fertilization Contact and recognition between sperm and egg -- quality control (same species) Regulation of sperm entry into the egg -- quantity control (essential that only a single sperm fertilizes egg) Fusion of genetic material of sperm and egg -- yields diploid cell (zygote) Activation of egg metabolism to initiate development ...
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