Chapter 1 student - Defining Biochemistry Biology Medicine...

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Defining Biochemistry Answers 1 MCDB310 – Chapter 1: Foundations of Biochemistry Biology Medicine Chemistry
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Metabolism: Life Involves Lots of Chemistry 2 MCDB310 – Chapter 1: Foundations of Biochemistry simple molecules complex biomolecules ATP [H] catabolism anabolism complex biomolecules simple molecules
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Chemical Composition of the Human Body Dry weight of a human body consists of: 1. Carbon (C) 60% 2. Nitrogen (N) 11% 3. Oxygen (O) 9% 4. Hydrogen (H) 6% Bulk elements: Na, K, Cl, S, Ca, P Trace Elements: Fe, Co, Cu, Zn 3 MCDB310 – Chapter 1: Foundations of Biochemistry
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Carbon central to nearly all compounds in the world >90% of the known 13 million compounds are carbon containing ( organic ) 4 MCDB310 – Chapter 1: Foundations of Biochemistry Why? Carbon is very versatile
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Carbon 5 MCDB310 – Chapter 1: Foundations of Biochemistry 4 unpaired electrons - can share them with 4 different partners can form single bonds with hydrogen can form single and double bonds with oxygen and nitrogen
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Carbon 6 MCDB310 – Chapter 1: Foundations of Biochemistry Greatest significance: carbon - carbon bonds Single carbon-carbon bonds (e.g. in amino acids) Double and triple carbon-carbon bonds (e.g. in fatty acids): shorter bond length rigid, no rotation possible
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Carbon 7 MCDB310 – Chapter 1: Foundations of Biochemistry Organic compounds: Molecules with covalently bonded carbon backbones (linear, branched or cyclic) Functional Groups: Groups of other atoms that are linked to carbon backbone (determine physical and chemical properties)
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Functional Groups Involving Oxygen 8 MCDB310 – Chapter 1: Foundations of Biochemistry
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Functional Groups Involving Hydrogen 9 MCDB310 – Chapter 1: Foundations of Biochemistry
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Functional Groups Involving Nitrogen 10 MCDB310 – Chapter 1: Foundations of Biochemistry (e.g. His) (e.g. Arg)
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Functional Groups Involving Sulfur 11 MCDB310 – Chapter 1: Foundations of Biochemistry
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Functional Groups Involving Phosphorus 12 MCDB310 – Chapter 1: Foundations of Biochemistry Phosphoanhydride
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Amino Acids: The Building Blocks of Proteins 13 MCDB310 – Chapter 1: Foundations of Biochemistry
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The Building Blocks of Nucleic Acids 14 MCDB310 – Chapter 1: Foundations of Biochemistry
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The Building Blocks of Lipids 15 MCDB310 – Chapter 1: Foundations of Biochemistry
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1. Amino acids (20 different L-amino acids)
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This note was uploaded on 04/05/2009 for the course MCDB 310 taught by Professor Walter during the Spring '09 term at University of Michigan.

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Chapter 1 student - Defining Biochemistry Biology Medicine...

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