KitcherCh5therapies-s09.ppt", filename="KitcherCh5therapies-s09.ppt", filename="

KitcherCh5therapies-s09.ppt", filename="KitcherCh5therapies-s09.ppt", filename="

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1 Kitcher, Ch. 5 "A Patchwork of Therapies"
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2 Definition: Genetic Disease People who bear a particular assemblage of alleles and grow up in standard environments invariably manifest the symptoms. (Kitcher, p. 107)
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3 "Standard Environments" Circumstances in which people normally live normal foods paths of daily activities other factors (Kitcher, p. 107)
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4 Places to intervene in therapy DNA RNA Protein Metabolism Nutrition gene therapy
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5 Places to intervene in therapy DNA RNA Protein Metabolism Nutrition PKU
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6 PKU-Phenylketonuria Gene defect Missing enzyme, can't metabolize amino acid phenylalanine Change diet to remove phenylalanine
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7 Places to intervene in therapy DNA RNA Protein Metabolism Nutrition Wilson's disease
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8 Wison's disease Genetic disease; not sex-linked Gene for Wilson's disease (ATP7B) maps to chromosome 13 Defect in copper-binding regions in cells (part of a transmembrane pump called a P-type ATPase)
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