Endocrine System

Endocrine System - The Endocrine System OBJECTIVES:...

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The Endocrine System OBJECTIVES: Describe the location and structure of the pituitary gland , and explain its structural and functional relationships with the hypothalamus . Describe the location and structure of several other endocrine glands, including: Thyroid / Parathyroid glands Adrenal gland Pancreas Several others Identify the hormones produced by each of the endocrine glands and specify the functions of those hormones.
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The Endocrine System Intercellular Communication
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The Endocrine System What are hormones and what do they do? Chemical messengers that travel via bloodstream Bind to RECEPTORS either on surface or or inside target cells Have widely varying effects on target cells Receptors on on surface of cell surface of cell membrane membrane of target cells activate SECOND MESSENGERS inside target cell 4. Second messenger causes various effects inside the postsynaptic cell 1. HORMONE HORMONE binding causes receptor to activate G-PROTEIN 2. G-protein turns on enzyme 3. Enzyme make “second messenger” HORMONE
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The Endocrine System What are hormones and what do they do? Chemical messengers that travel via bloodstream Bind to RECEPTORS either on surface or or inside target cells Have widely varying effects on target cells Receptors inside target inside target cells cells can directly affect genetic machinery or other intracellular processes
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The Endocrine System Overview of Endocrine Organs
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Hypothalamus and Pituitary Gland Command central of the endocrine system Arcuate & Periventricular nuclei
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Hypothalamus and Pituitary Gland Supraoptic and Paraventricular Nuclei Neurons make hormones Release into bloodstream at capillary bed of POSTERIOR PITUITARY HORMONES INVOLVED: Antidiuretic Hormone (ADH) • Also called vasopressin • Made in both hypothalamic nuclei • Causes increased water uptake by kidneys Oxytocin (OT) Oxytocin (OT) • Made in both hypothalamic nuclei • IN FEMALES contraction of uterus during labor and milk ejection during suckling • IN MALES contraction of ductus deferens
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Endocrine System - The Endocrine System OBJECTIVES:...

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