Lecture 4 Mendel Notes

Lecture 4 Mendel - Announcements 1/23 Quiz 2 posted due 1/28 Clarification in notes about DNA Pol I 1 Mechanisms to maintain fidelity during

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Announcements… 1/23 Quiz 2 posted due 1/28 Clarification in notes about DNA Pol I 1
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Mechanisms to maintain  fidelity during replication Hydrogen bonding of the incoming  base Proofreading after the insertion site  based on the shape of mismatch  3’ -> 5’ exonuclease activity Degradation of the RNA primer with 5’  -> 3’ exonuclease activity
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Learning objectives… 1. Explain how we know genes encode  enzymes (Beadle and Tatum’s  experiment).  2. Construct and analyze simple  pedigrees. 3. Evaluate Mendelian inheritance  patterns. 4. Explain how genotypes relate to  phenotypes in Mendelian patterns of  inheritance.
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Mendelian inheritance in  humans Most traits in humans are due to the  interaction of multiple genes and do  not show a simple Mendelian pattern of  inheritance. A few traits represent single-genes.  
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This note was uploaded on 04/05/2009 for the course BIOL 202 taught by Professor Kieber-hogan during the Spring '08 term at UNC.

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Lecture 4 Mendel - Announcements 1/23 Quiz 2 posted due 1/28 Clarification in notes about DNA Pol I 1 Mechanisms to maintain fidelity during

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