ch3&5.9.22post

ch3&5.9.22post - Howneuronscommunicate atthesynapse...

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How neurons communicate at the synapse Key terms: Synaptic cleft or “synapse” Neurotransmitter Reuptake Storage Vesicles Receptor sites binding
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Drugs alter Neurotransmitter Activity Two Mechanisms: Agonist Antagonist
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Tying Neurotransmitters and Drugs together QuickTimeª and a TIFF (Uncompressed) decompressor are needed to see this picture. Key-in-lock metaphor: Drugs happen, or, are built, to have similar shapes as neurotransmitter or hormone molecules. Receptors will only respond to a certain shape of molecule.
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Neurotransmitters are Excitatory or Inhibitory Excitatory Neurotransmitters Ex : Glutamate Facilitates sensation, learning Alcohol blocks glutamate Stimulant drugs include: These increase other excitatory neurotransmitters:
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Inhibitory Neurotransmitters Ex: GABA (gamma aminobutyric acid) Substances that increase GABA: Alcohol Prescription medications: Anti-epileptics Benzodiazepines Barbiturates “Sedative-hypnotics”
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ch3&5.9.22post - Howneuronscommunicate atthesynapse...

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