Lect21 - Heritable information can be changed by horizontal...

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Unformatted text preview: Heritable information can be changed by horizontal transfer Learning Goals Students will understand the difference between vertical and horizontal transfer of DNA. Students will understand that DNA can be transferred between bacteria, and that this DNA is often not chromosomal. Students will understand that horizontal transfer of DNA is one mechanism of evolution. Students will be able to describe the modes of DNA transfer. transduction transformation conjugation Students will be able to discriminate when they would most likely be used in nature and in the laboratory. Students will also recognize that some DNA elements, such as transposons and insertion sequences, can jump into the chromosome and cause mutations. Students will understand that if the DNA that transfers into a cell is homologous to DNA in the chromosome, the transferred DNA can recombine into the chromosome. Students will be able to link this to what they learned about recombination in lecture 20. Students will be able to apply this to mock laboratory experiments, such as what they confront in the case study. Click to edit Master subtitle style Genome: The complete genetic Vertical transfer : by replication and cell division Horizontal transfer : other than by reproduction e.g.,., daughter cells inherit copy of parental chromosome e.g., cell in population obtains a plasmid Chromosome Large stretch of DNA Haploid - 1 copy per cell Codes for essential genes Often circular Can be linear Some microbes have more than one More about Bacterial Genomes R. sphaeroides chromosomes strain 2.4.1 Characteristic G:C content Genome Size Carsonella ruddii ; ~0.2 Mb (Smallest microbial genome) E. coli ; ~4 Mb Human; ~3,600 Mb But....
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This note was uploaded on 04/07/2009 for the course MICROBIO 303 taught by Professor Kaspar/escalnte/downs during the Spring '09 term at Wisconsin.

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Lect21 - Heritable information can be changed by horizontal...

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