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19 - nutri sci 11/19 Vitamin A precursors as protective...

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nutri sci 11/19 15:58 Vitamin A precursors as protective factor Blood levels of beta-carotene correlate with cancer risk Beta Fits with the anti-oxidant hypothesis very well o A lot of anti-oxidants in diet will have less free radicals=lower risk of cancer Carotenoids o <1/3 of US vit A intake from carotenoids o 500 carotenoids in nature o yellow/orange F/ V: beta-carotene o dark leafy greens: lutein o tomatoes: lycopene o lutein and lycopene highest in blood beta-carotene trails large clinical trials finish study of 29,000 male smokers  beta-carotene and vitamin E failed to protect against lung cancer o 1 group beta-carotene o 1 group vitamin E o 1 groupd  both o 1 group  placebo
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one trial showed beta-carotne increased cancer phytochemicals (phytonutrients) found associated with carotenoids carotenoids may be a marker for agents responsible for edipemiological  findings 10,000 chemicals in a tomato studied in animals and cell-culture carcinogenesis  carcinogens chemicals which damage DNA and initiate cancer industrial exposure o vinyl chloride o asbestos o pesticides food carcinogens nitrates—nitrosamines o bacon, beer
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