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36 2006 Dee U. Silverthorn LAB 3: CARDIOVASCULAR REFLEXES OUTLINE OF ACTIVITIES I. Blood Pressure (Baroreceptor) Reflex Computer Exercise II. Valsalva Maneuver III. Cold Stress Pressor Test OBJECTIVES 1. Learn the components of the baroreceptor reflex. 2. Explain physiological compensation for orthostatic hypotension. 3. Predict and demonstrate changes cardiovascular function due to stimuli such as increased intrathoracic pressure and cold stress. I. BLOOD PRESSURE (BARORECEPTOR) REFLEX Computer Exercise The previous labs were concerned with understanding the basic anatomy of and the flow of blood through the heart and circulatory system, and how to measure electrical events and (indirectly) mechanical events of the heart via electrocardiography and sphygmomanometry, respectively. All of these events and functions are regulated via autonomic output controlled by the cardiovascular control center (CVCC) in the medulla oblongata. The primary function of the CVCC is to maintain adequate blood flow to the brain and heart. Sensory input to this integrating center comes from a variety of peripheral sensory receptors, primarily stretch- sensitive baroreceptors located in the walls of the carotid arteries and the aorta (Silverthorn, 2007). In this computer exercise, you will review or learn the basic components of the baroreceptor reflex. In addition, you will learn how the interneurons in the CVCC convert a single signal from the baroreceptors into a dual autonomic signal that does not cancel effects. Before you begin, read through “Regulation of Blood Pressure” in your textbook (Silverthorn, 4e, pp. 521-524). Open the program “Blood Pressure Reflex” on the desktop. The program begins with an introduction to a problem involving orthostatic hypotension, and is menu-driven. Your TA will demonstrate how to get started. In addition , a few tips are included below: Tips: 1. The default neuron is an interneuron(e). The cell body is round and the axon terminal is the triangle. Drag it into place first. 2. To change to another neuron type, double-click the round cell body. This opens a selection box. 3. To switch a neuron from excitatory (open triangle) to inhibitory (solid triangle), double-click the axon terminal.
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37 2006 Dee U. Silverthorn 4. The RAISE BP box at lower right is the stimulus. Clicking it causes BP to increase, and the pathway shows the response to increased BP. You may look at low BP as a stimulus by clicking on the illustration of the man lying down. 5.
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This note was uploaded on 04/09/2009 for the course BIO 416L taught by Professor Lagowski during the Spring '08 term at University of Texas.

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