1 BIO 326R Intro - BIO 326R Introduction Microbiology What...

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BIO 326R  Introduction
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Microbiology – What is it?  The Study of small organisms (less than about 1mm) Includes Bacteriology, Immunology, Virology, etc
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Why Study Microbiology Diseases Environment Technology Industry
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Pasteur Swan necked flasks – no spontaneous generation Pasteurization
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Robert Koch – Microbes cause diseases Working on Anthrax, a disease caused by Bacillus anthracis Transferred disease injecting diseased tissue into healthy mice Place diseased spleen from mice in broth Isolated bacteria from tissue by growing in broth Bacteria produced anthrax when injected into healthy mice (no tissue present)
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Koch’s Postulates Microorganism is present in every case of the disease, but absent in healthy organisms Microorganism is not found in healthy organisms Suspected microorganism must be isolated and grown in a pure culture The same disease occurs when the isolated microorganism is inoculated into a healthy host The same microorganism must be isolated again from the diseased host
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1 BIO 326R Intro - BIO 326R Introduction Microbiology What...

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