Lecture04b_bio201_f07[1]

Lecture04b_bio201_f07[1] - ARIZONA STATE UNIVERSITY Lecture...

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Human Human Anatomy Anatomy SEVENTH EDITION SEVENTH EDITION Elaine N. Marieb Elaine N. Marieb Katja Hoehn Katja Hoehn ARIZONA STATE UNIVERSITY Lecture Series 3 Lecture Series 3
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Bio 201 ASU DPC J. Active Transport Uses ATP to move solutes across a membrane Requires carrier proteins
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Bio 201 ASU DPC J. Types of Active Transport Symport system – two substances are moved across a membrane in the same direction Antiport system – two substances are moved across a membrane in opposite directions
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Bio 201 ASU DPC J. Types of Active Transport Primary active transport – hydrolysis of ATP phosphorylates the transport protein causing conformational change Secondary active transport – use of an exchange pump (such as the Na + -K + pump) indirectly to drive the transport of other solutes
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Bio 201 ASU DPC J. Types of Active Transport
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Bio 201 ASU DPC J. Vesicular Transport Transport of large particles and macromolecules across plasma membranes Exocytosis – moves substance from the cell interior to the extracellular space Endocytosis – enables large particles and macromolecules to enter the cell
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Bio 201 ASU DPC J. Vesicular Transport Transcytosis – moving substances into, across, and then out of a cell Vesicular trafficking – moving substances from one area in the cell to another Phagocytosis – pseudopods engulf solids and bring them into the cell’s interior
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Bio 201 ASU DPC J. Vesicular Transport Fluid-phase endocytosis – the plasma membrane infolds, bringing extracellular fluid and solutes into the interior of the cell Receptor-mediated endocytosis – clathrin-coated pits provide the main route for endocytosis and transcytosis Non-clathrin-coated vesicles – caveolae that are platforms for a variety of signaling molecules
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Bio 201 ASU DPC J. Exocytosis
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Bio 201 ASU DPC J. Clathrin-Mediated Endocytosis Cytoplasm Extracellular fluid Extracellular fluid Plasma membrane Clathrin- coated pit Plasma membrane Ingested substance (a) Clathrin-mediated endocytosis
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Bio 201 ASU DPC J. Clathrin-Mediated Endocytosis Cytoplasm Extracellular fluid Extracellular fluid Plasma membrane Detachment of clathrin- coated vesicle Clathrin- coated vesicle Clathrin- coated pit Plasma membrane Ingested substance (a) Clathrin-mediated endocytosis
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Bio 201 ASU DPC J. Clathrin-Mediated Endocytosis Cytoplasm Extracellular fluid Extracellular fluid Plasma membrane Detachment of clathrin- coated vesicle Clathrin- coated vesicle Uncoating Uncoated vesicle Uncoated vesicle fusing with endosome Endosome Clathrin- coated pit Plasma membrane Ingested substance Clathrin protein (a) Clathrin-mediated endocytosis
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Bio 201 ASU DPC J. Clathrin-Mediated Endocytosis
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This note was uploaded on 04/29/2008 for the course BIO 201 taught by Professor Oberstein during the Fall '08 term at ASU.

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Lecture04b_bio201_f07[1] - ARIZONA STATE UNIVERSITY Lecture...

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