Handout+_3 - Handout#3 1 Match the following steps in AP to...

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Handout #3 1. Match the following steps in AP to the numbers above __2__ Na+ channels inactivate __0__ Resting potential of the cell __2__ K+ channels open __2__ The ball on the chain plugs the channel __3__ Cell hyperpolarizes __3__ K+ channels close __1__ Na+ channels open __4__ Cell returns to resting potential __1__ Threshold Depolarization from step _0 or 1__ to step _2__ Repolarization from step _2__ to step _3__ Absolute refractory period from step _2__ to step _4__ Relative refractory period at step _3__ 2. Put the following in order as they happen during an AP. K+ leaves the cell 5 Na+ channels inactivate 3 Na+ channels open 1 K+ channels open 4 Na+ channels are closed 0 K+ channels close 6 Na+ enters the cell 2 Resting potential 0
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3. Tetrodotoxin (TTX) is a very potent neurotoxin with no known antidote. It blocks voltage gated Na+ channels. What effects would TTX have on AP? There would be no depolarization and therefore no AP in the presence of TTX. 4. Multiple Sclerosis (MS) is a neurodegenerative autoimmune disorder in which one's immune system starts to attack its own myelin sheath that surrounds the axons.
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