Lecture 10 - Meiosis (Fitch) 10-10

Lecture 10 - Meiosis (Fitch) 10-10 - Meiosis Principles of...

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Meiosis Principles of Biology Lecture 10 Prof. David Fitch
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Heredity A major feature of life Heredity = passing on features from one generation to another sometimes agenetic genetic Variation implies that heredity is not "perfect" environmental developmental genetic How does it work?
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Last time: mitosis Diploid cells have 2 sets of genomes (2n) Interphase (S-phase): DNA is replicated produces "sister chromatids" Chromosomes are packaged Chromosomes align at metaphase plate Sister chromatids are segregated to daughter cells Mitosis simply copies ("clones") the genome: 2n 2n
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Result of cell division: clones Replication Equal distribution of genetic material Diploidy Clones Cytokinesis Mitosis 2n 2n 2n Mother Cell Diploid Diploids 2n 2n Diploids 2n 2n Diploids Daughter Cells
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Mitosis vs. Meiosis Meiosis only in germ cells Result is haploid cells (1n) 2n 2n 2n Mother Cell diploid (homologs segregate) 1n 1n haploids 1n 1n haploids Crossing-over & segregation Mitosis-like sep. of copies
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Fertilization restores diploidy Sexual reproduction Fertilization = fusion of two haploid gametes to form a diploid zygote Development = mitotic cleavage n +n 2n 2n 2n n n
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Outline of concepts How are the haploid gametes produced? meiosis Fertilization restores diploidy What are the consequences of meiosis and fertilization? Genetic Evolutionary Are meiosis and fertilization essential for higher organisms?
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Human sexual life cycle Alternation of stages Individuals are diploid Gametes are haploid generally true. .. Key Haploid ( n ) Diploid (2 n ) Haploid gametes ( n = 23) Ovum ( n ) Sperm Cell (n) MEIOSIS FERTILIZATION Ovary Testis Diploid zygote (2 n = 46) Mitosis and development Multicellular diploid adults (2 n = 46)
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Alternation of stages: difference in emphasis Diploid
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This note was uploaded on 04/29/2008 for the course BIO V23.0011 taught by Professor Fitch during the Spring '08 term at NYU.

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Lecture 10 - Meiosis (Fitch) 10-10 - Meiosis Principles of...

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