BIO 320 Lecture11_2009slides

BIO 320 Lecture11_2009slides - The origin of Mitochondria...

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1 BIO320 - Lecture 11 02/26/2009 IMPORT OF PROTEINS INTO MITOCHONDRIA ***OPTIONAL READING: review article*** content: gene loss and transfer to the nucleus Molec. Phylogenet. Evol. 29:380-395 Downloadable @ blackboard The origin of Mitochondria and Chloroplasts Alberts 12-4 Mitochondrial Organization •Has its own: • genome • tRNA • rRNA = ribosome •Encodes some mitochondrial proteins •Most mitochondrial proteins encoded in the nucleus Karp 5.3 The outer membrane of mitochondria and bacteria have the channel protein “porin” Allows the passage of small metabolites (H + , ions, ATP, NAD, CoA) but NOT of large proteins See Alberts Figure 10-26 The mitochondria contains all enzymes used in the TCA cycle and oxidative phosphorylation Alberts 14-10 The electron transport chain is a set of three proton pumps that use the energy of NADH to move protons out of the matrix Alberts 14-14
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BIO 320 Lecture11_2009slides - The origin of Mitochondria...

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