BIO 320 Lec18.2009.notes

BIO 320 Lec18.2009.notes - Lecture 18 Extracellular Matrix...

Info icon This preview shows pages 1–3. Sign up to view the full content.

1 Lecture 18 Extracellular Matrix: Interactions between Cells and Their Environment Figure 19-3 Molecular Biology of the Cell (© Garland Science 2008) Gap Junction Mediate intercellular communication Cells come close, but do not contact. “pipelines” made by connexon proteins that span the membrane Karp 7.32 Gap junction: connexon Karp 7.32, see alberts19-34 Central opening: 1.5 nm in diameter Non-selective: Allows passage of <1000 Dalton particles Closure regulated: phosphorylation Two General Types of Cell Junctions in Epithelial Cells cell-cell junctions cell-matrix junctions function seal anchor anchor communicate anchor Figure 19-18 Molecular Biology of the Cell (© Garland Science 2008)
Image of page 1

Info icon This preview has intentionally blurred sections. Sign up to view the full version.

2 Another Cell-substrate junction: the hemidesmosome Karp, 7.18 -at basal surfaces of epithelial cells “spot welds” between Epithelial cells and the underlying extracellular space in out The hemidesmosome -Integrins connect ECM with intermediate filaments (I.e. keratin) An example: connect the epidermis with the dermis Contain: Intermediate filaments Anchor into plaque w/ plectin + dystonin AND integrin
Image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern