BIO 320 Test1-2008 - BIO-320 Cell Biology Spring 2008...

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BIO-320 Name _____________________________________ Cell Biology – Spring 2008 --------------------------------------------------------------------------------------------------------------------- PERSONAL EID __________________ Multiple choice________ Fill in + Essays________ TOTAL SCORE ________ Page 1 of 9 FIRST MIDTERM EXAM (02/19/08) Before you do anything else, please: Check to make certain that your copy of the exam is complete, i.e. pages 1 -9. Print your name legibly in the space provided at the top of each page, and also on the scantron bubble sheet. BE SURE TO FILL IN YOUR EID IN THE CORRESPONDING SPACES IN THE SHEET AND ON THIS PAGE. Total possible points = 100 points. The essays MUST be written in pen. If you use a pencil you cannot request a regrade. MULTIPLE CHOICE [2.5 points/question] Choose the best answer for the 30 multiple-choice questions by marking the appropriate letter under the same number on your scantron bubble sheet. USE A # 2 PENCIL. 1) Eukaryotic cells differ from prokaryotic cells in several ways. Which of the following statements is TRUE? a) Prokaryotic cells do not have a plasma membrane. b) Prokaryotic cells do not use RNA to encode the information for proteins c) Prokaryotic cells do not have mitochondria. d) Prokaryotic cells do not have ribosomes. e) Prokaryotic cells do not use amino acids to make proteins. 2) Which of the following bonds in a protein is cleaved /broken by a protease? a) peptide bonds b) hydrogen bonds c) hydrophobic bonds d) cysteine bonds e) ionic bonds 3) Which of the following statements is TRUE about reactions catalyzed by a kinase? a) Kinases use ATP to generate energy b) Kinases can add a phosphate to the amino acid arginine c) Kinases can turn protein activities off d) Kinases can remove phosphate from proteins e) Kinases add a phosphate onto ADP to generate ATP 4) Which of the following would increase the resolution of a microscope? (Two answers) a) increasing the numerical aperture of the objective lens b) decreasing the wavelength of the light used to illuminate the object c) using a fluorescently-labeled secondary antibody to detect an antibody d) using a laser pinhole to focus on a single point e) labeling a protein with green fluorescent protein
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BIO-320 Cell Biology – Spring 2008 Name _____________________________________ Page 2 of 9 5) Which of the following amino acids is MOST likely to be in the transmembrane domain of an integral membrane protein? a) Serine b) Asparagine c) Lysine d) Aspartic Acid e) Leucine 6) Which of the following statements about phosphorylated proteins is TRUE: a) Phosphorylated proteins are always turned ON. b) Rab-GDP is phosphorylated to become Rab-GTP c) Phosphorylation of proteins denatures their structure d) Proteins can be phosphorylated on Ser amino acids e) Phosphorylation changes the primary sequence of a protein 7) Bilayers in membranes form primarily because of: a) Hydrophobic interactions between fatty acid tails of phospholipids
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BIO 320 Test1-2008 - BIO-320 Cell Biology Spring 2008...

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