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lecture notes 2-13 mri - technology used in nuclear...

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Professor Marc Walters – "Clinical Molecular Imaging, From X-Rays to MRI" February 13, 2008 Marc Walters is a professor in the NYU chemistry department whose research is concerned with designing contrast agents for MRI ( magnetic resonance imaging) image enhancement. His February 13 th lecture, "Clinical Molecular Imaging, From X-Rays to MRI,” covered various types of clinical imaging equipment and contrast agents and their uses in a medical setting. Professor Walters’ own work deals with MRI and the chemicals involved in their imaging process, and thus focused his lecture on these topics. Though some people associate any kind of clinical imaging with use of radiation (probably because it is utilized by both CT and x-ray imaging), MRI actually uses a magnetic field and the unique properties of the hydrogen atoms in the human body. There are many variations of what you and I might think of as a basic MRI machine – today’s MRI grew out of the
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Unformatted text preview: technology used in nuclear resonance imaging-“nuclear resonance imaging” (chem laboratory) vs. “magnetic resonance imaging” (makes people feel more comfortable)-Sitting MRI, “MRI operating room”-Chemical “marker” – contrast agent- provides a way for clinician to detect differences between tissues (sometimes there is no contrast ) - development of contrast agents and new magnets means physicists, biologists, etc. are all involved in MRI research & development-Injection of contrast agent means procedure ceases to be non-invasive (injection of dye)-FDA approval of contrast agents (effective “complexation” needed to eliminate the toxicity – “wrapping” an ion in another chemical – aka gadolinium, which would replace calcium in body if it wasn’t “wrapped” with other chemicals for stability-...
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  • Spring '08
  • CASScholars
  • Magnetic resonance imaging, Medical imaging, MRI, Contrast Agents, Clinical Molecular Imaging, nuclear resonance imaging

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