Problem Set 7 questions

Problem Set 7 questions - CELL BIOLOGY PROBLEM SET 7 1....

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  CELL BIOLOGY PROBLEM SET 7   1. What was 8-azido cAM32P used for as discussed in class? What type of molecule is this and how does it work? Regulatory Units Bind cyclic AMP o cAMP analogs o 8- azido cAMP 32 Photoaffinity Analogs 2. One of the key words describing the cAMP second messenger pathway is "amplification". Why is this term appropriate? 3. How does calcium act as a second messenger with reference to the following: a. calmodulin Calcium calmodulin Calcium binding proteins o EG Calmodulin b. Protein Kinase C Protein Kinase C (IP3 DAG) GPCR o There is a g protein, hence, start with GPCR Bind to the affector Phosolipase C Not adenocyclase Has a target substrate, a specific phospholipids o IP3 binds to ER o Increase of Calcium from Endoplasmic Reticulum o DAG binds to PKC  o Cell Membrane channels have to open 4. The following are drugs that affect the cAMP system. Describe how each one of them
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This note was uploaded on 04/13/2009 for the course BIOL 311 taught by Professor Vanbuskirk during the Spring '08 term at Binghamton University.

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Problem Set 7 questions - CELL BIOLOGY PROBLEM SET 7 1....

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