CR10 - Reading for 3 mammal lectures Chapters 5, 6 From...

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Reading for 3 mammal lectures •Chapters 5, 6 •From before: 168-189; 196-206 •Add: 159-167; 192-196; 207-8 Objectives •To understand how SCN controls –Locomotor activity –GnRH –Melatonin •To understand why 2 oscillators have been invoked •To see continuities across species Hypothetical Projections From SCN to Time Various Functions
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Successful transplants •Contained Calbindin containing cells •Had to be near SCN region •Didn’t seem integrated into host •Why is only activity rhythm restored? Diffusible signal •Present in the SCN area •Regulated by clock genes •Should respond to light entrainment •Receptor near SCN •Exposure to molecule should affect behavior
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Transforming growth factor - alpha Epidermal growth factor
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•Every 4th d, female rodent is “receptive” •Every 4th d, surge of LH •Same time of day •Is this caused by the circadian clock? •GnRH releases LH •Only get LH surge when hormones are right •Can get daily LH surges Estrous cycle Serum LH During Hamster Estrous Cycle
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CR10 - Reading for 3 mammal lectures Chapters 5, 6 From...

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