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mcII05e2 - MEDICINAL CHEMISTRY II EXAM#2 April 1 2005 Name...

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MEDICINAL CHEMISTRY II EXAM #2 April 1, 2005 Name Med. Chem Number SECTION A. Answer each question in this section by writing the letter corresponding to the best answer on the line provided (2 points each; 50 points total) 1. The drug illustrated below: O CH 3 CH 2 CH 2 CH 2 C O CH 2 CH 2 N H Cl I Is a benzoate ester local anesthetic II Cannot penetrate into neurons because it is 100% charged at all pH values III Is used as a topical local anesthetic on mucous membranes and is sold over the counter a) I only b) III only c) I and II only d) II and III only e) I, II, and III Answer 2. The drug illustrated below is: O HO N CH 3 H O H I Can be addicting II Is a µ -agonist III Is used to treat pain 3. The drug illustrated below: O HO N CH 2 OH O H CH Cl H CH 2 I Can reverse respiratory depression resulting from an overdose of opioid narcotics II Is most effective when given orally III Is a potent µ -agonist
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