McI06e2 - 1 Medicinal Chemistry 409 Name Med Chem November 3 2006 THERE ARE TWELVE PAGES IN THIS EXAM Select the best answer for each of the

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1 Medicinal Chemistry 409 N a m e Med. Chem. # November 3, 2006 THERE ARE TWELVE PAGES IN THIS EXAM Select the best answer for each of the following (30 Questions, 2 Points each): 1. The drug illustrated below: N HO H Cl I Can cross the Blood Brain Barrier II Is an anticholinergic agent III Can cause miosis a. I only b. III only c. 1 and II only d. II and III only e. I, II, and III Answer 2 The drug illustrated below is: N HN CH 2 I A potent peripheral vasodilator II Used as a nasal decongestant III An α 1 -agonist a I only b III only c I and II only d II and III only e I, II, and III Answer 3. The drug illustrated below is: I A calcium channel blocker II Can be used as an antiarrhythmic agent. III Can be used to treat hypertension. OCH 3 OCH 3 CCN (CH 3 ) 2 CH CH 2 CH 2 CH 2 N CH 3 CH 2 CH 2 OCH 3 OCH 3 a I only b III only c I and II only d II and III only e I, II, and III Answer
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2 . The drug illustrated below: 4 HO HO CH 2 C NH 2 H COOH I Is a potent dopa decarboxylase inhibitor II Is used to treat Parkinson’s disease. III Can be metabolized to dopamine. a I nly Answer o b III only c I and II only d II and III only e I, II, and III . The drug illustrated below: I Can be used to treat Alzheimer’s disease. holinergic agent. 5 II Is an anticholinergic agent. III Is primarily a direct-acting c a I only Answer b III only c I and II only d II and III only e I, II, and III . The drug illustrated below is: I An α 1 -agonist ng cholinergic agonist 6 II An indirect-acti III Used to treat Alzheimer’s disease. a. I only nly Answer b. III only c. I and II o d. II and III only e. I, II, and III 7. The drug il trate H CH 2 NH C(CH 3 ) 3 lus d below: O 2 OH OH C OH I . Increases heart muscle contraction II Is used to treat hypertension III Is a non-selective β -blocker a I only e I, II, and III Answer b III only c I and II only d II and III only 3 CHCH 2 N CH 3 3 3 O C NH 2 O Cl Cl N 3
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3 8. The dru llust I Is an anticholinergic agent II Can cause miosis g rated below: i III Is a cholinergic agonist a I only b III only Answer c I and II only d II and III only e I, II, and III 9. The dru llust g i rated below: H CH 3 N CH 2 CCH II CH 3 noami O-B). Is used to treat hypertension. I o ne oxidase inhibitor (MA Is a selective m III Cannot cross the Blood Brain Barrier. a I only b III only Answer c I and II only d II and III only e I, II, and III 10. The dru llust g i rated below is: O CH CH N C 2 C H Cl O CH 2 CH 3 2 2 H 2 SO 2 NH 2 OCH 3 I Used to uced asthma plasia H H prevent exercise-ind II Used to treat the symptoms of Benign Prostatic Hyper III An α 1a -antagonist.
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This note was uploaded on 04/14/2009 for the course 663 701 taught by Professor Arnold,e. during the Spring '09 term at Rutgers.

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McI06e2 - 1 Medicinal Chemistry 409 Name Med Chem November 3 2006 THERE ARE TWELVE PAGES IN THIS EXAM Select the best answer for each of the

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