motivation%20slides

motivation%20slides - NEURO 1 NOVEMBER 13, 2007 MOTIVATION...

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NEURO 1 NOVEMBER 13, 2007 MOTIVATION
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Why we need to drink water - #1. To maintain normal concentrations of ions, proteins etc. inside and outside the cell. Therefore, it should come as no surprise that the state of cellular hydration is involved in the control of drinking. OSMOMETRIC THIRST Diego Rivera, El Agua, Origen de la Vida, 1951
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Response to increased osmolarity (hypertonicity) of the blood *organum vasculosum of the lamina terminalis Detected by OVLT* neurons Vasopressin or ADH released by posterior pituitary ADH causes kidney to conserve water “osmometers”
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Why we need to drink water - #2 To maintain blood volume blood pressure, perfusion of the brain, heart, kidney and other organs. Therefore, it should come as no surprise that the brain, heart, kidneys and certain other organs are involved in the control of drinking behavior. VOLUMETRIC THIRST Heart Kidney Brain A 70 kg male has about 5 liters of blood in his body.
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Injected into the brain, angiotensin II is one of the most potent known dipsogens , i.e. inducers of thirst. Sensors in the heart and great vessels detect decreased blood pressure, signal NTS. NTS signals the hypothalamus to activate the sympathetic system. Peripheral arterioles constrict, heart beats faster. Cardiac phase Kidney detects decreased blood flow and releases renin Angiotensin II Angiotensin II acts on hypothalamus. Vasopressin acts on kidney to conserve
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This note was uploaded on 04/29/2008 for the course NEUR 10 taught by Professor Stein/paradiso during the Fall '07 term at Brown.

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motivation%20slides - NEURO 1 NOVEMBER 13, 2007 MOTIVATION...

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