Chapter 19 - 1 204-325 2 Summary of the Last Lecture h h...

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Unformatted text preview: 1 204-325 2 Summary of the Last Lecture h h Genomics is the science of mapping, Genomics is the science of mapping, sequencing, comparison and functional analysis sequencing, comparison and functional analysis of the entire genomes of organisms. of the entire genomes of organisms. h h Map Map-- based genome sequencing uses orderly based genome sequencing uses orderly mapped DNA fragments for sequencing. The mapped DNA fragments for sequencing. The assembly of sequencing data is straightforward. assembly of sequencing data is straightforward. h h Shotgun genome sequencing uses random, Shotgun genome sequencing uses random, overlapping DNA fragments for sequencing. overlapping DNA fragments for sequencing. The assembly of sequencing data needs special The assembly of sequencing data needs special algorithm and enormous computing power. algorithm and enormous computing power. h h DNA microarray is a new technique for gathering DNA microarray is a new technique for gathering large amount of genetic data in parallel. large amount of genetic data in parallel. 3 1. Induction of lac Operon 2. Positive Regulation of lac Operon 3. Attenuation of trp Operon Todays Topics 4 Topic 1 Induction of Induction of lac lac Operon Operon 5 General Organization of an Inducible Gene Operator 6 Initiation 0f Transcription from Promoter (Chapter 13) 7 -Independent Termination of Transcription (Chapter 13) 8 Concept of Transcriptional Regulation 9 The Structure of lac Operon and lacI Gene 10 Translation of the Polycistronic mRNA in lac Operon Polarity (Stop) 11 Functions of the lac Operon Gene Products (lacY gene product) (lacZ gene product) (lacZ gene product) 12 lac Operon in the Absence of Lactose : Off 13 Allosteric Shift of lac Repressor 14...
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This note was uploaded on 04/29/2008 for the course BIO SCI 325 taught by Professor Zang during the Spring '08 term at Wisconsin Milwaukee.

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Chapter 19 - 1 204-325 2 Summary of the Last Lecture h h...

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