Unformatted text preview: . a. RX and N 3 , followed by reduction. b. Gabriel synthesis. c. Reductive amination. d. Reduction of amides. e. Reduction of nitriles. f. Hofmann rearrangement. g. Reduction of nitro groups. III. Reactions of amines. Earlier units included discussion of amine acylation and alkylation. In addition, recall that amines may be used to form imines. A new reaction in this unit is the reaction of nitrous acid (HONO) and nitrosonium ions (NO + ) with amines. Know the products to be expected in the reaction of: a. HONO with primary amines. b. HONO with secondary amines. IV. Miscellaneous . a. The Hofmann Elimination was described and used to establish amine structure....
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- Spring '08
- pH, Amine, University of Pittsburgh Unit, I. Amine Basicity.