BCH Exm 3, glycolysis

BCH Exm 3, glycolysis - 1 LJ Glycolysis Chapter 17 in...

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1 LJ Glycolysis Chapter 17 in Campbell 2 LJ General features of glycolysis • First stage of glucose metabolism • Catabolic • Anaerobic process • Ends with production of pyruvate. • Under continued anaerobic conditions, pyruvate is converted to lactic acid and the lactic acid is excreted. • Net ATP production: 2/glucose 3 LJ Fate of pyruvate • Under aerobic conditions: In the presence of oxygen, pyruvate loses carbon dioxide The 2 remaining carbons become linked to coenzyme A This produces acetyl-CoA Acetyl-CoA enters the citric acid cycle (Krebs cycle). 4 LJ Fate of pyruvate, cont. Under anaerobic conditions (no oxygen present): 1. Fermentation: pyruvate loses C02 and becomes acetaldehyde. Further reduction produces ethanol. 2. More common: reduction to lactate. 3. Where such anaerobic metabolism is the only energy source (examples): a. Mammalian red blood cells. b. Lactobacillus in sour milk c. Canned foods tainted with Clostridium botulinum. 5
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BCH Exm 3, glycolysis - 1 LJ Glycolysis Chapter 17 in...

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