Lecture 1 - Lecture 1 Slide 1 Structure function paradigm...

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Lecture 1 Slide 1 Structure function paradigm Which part of the molecule is important Figure out what is involved in the mechanism Slilde 2 - How protein and genes get expressed - Central dogma is o DNA makes mRNA makes protein Slide 4 - DNA is a polymer - Interaction between nucleotides by H-bonding - Antiparalell Slide 5 - Tetrahedral carbons are not planar - Two options for ribose - Ribonucleic acid depend on the oxygens on the 3’ and 2’ position Slide 6 - Aromatic - Actually planar (ability to stack) - There hereral atoms in the 3,1 in pyrimidine and 1,3,9 for the purine - Ribose has prime, Dioxyribose has none Slide 7 - Purines o These are chemically similar (Adenine and Guanine) o Hydrogen bond donor Slide 8 - MEMORIZE THE NUMBERS AND POSITIONS OF DNA NUCLEOTIDES Slide 9 - When working with the dioxynucleotide is to include the d next to the named nucleotide (dA) Slide 10 - does not include a Deoxy- prefix in front of the name Slide 12 - 5-METHYLCYTIDINE: includes a ribose (methyl on the five position) - N6 – methyladensine (group on the six carbon)
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This note was uploaded on 05/01/2008 for the course BIOL 99 taught by Professor Cocco during the Spring '08 term at UC Irvine.

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Lecture 1 - Lecture 1 Slide 1 Structure function paradigm...

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