Levitsky lecture 11 - 20 40 60 80 100 120 140 3 6 9 1 2 1 5...

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Unformatted text preview: 20 40 60 80 100 120 140 3 6 9 1 2 1 5 1 8 2 1 2 4 Time (min) Blood Glucose (mg/100 dl) light-headed sympathetic fainting Blood Glucose Response alpha cell (glucagon) beta cell (insulin) glucagon glycogen glucose blood pancreas (alpha cells) glucagon glycogen glucose liver 20 40 60 80 100 120 Time Blood glucose (mg/dl) insulin glucagon insulin insulin insulin glucagon glucagon glucagon Problem alpha cell (glucagon) beta cell (insulin) delta cell (somatostatin) Reduces response to insulin and glucogon 20 40 60 80 100 120 140 3 6 9 1 2 1 5 1 8 2 1 2 4 Time (min) Blood glucose (mg/dl) Blood Glucose Response 1 hours blood liver hypothalamus sympathetic nervous system adrenal gland adrenal cortex adrenal medulla E luconeogenisis amino acids glucose Brain is happy. But how about muscle. No insulin! blood liver hypothalamus sympathetic nervous system adrenal gland adrenal cortex adrenal medulla luconeogenisis amino acids adipose cell FFA TG Hormone sensitive lipase blood liver hypothalamus adrenal gland...
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Levitsky lecture 11 - 20 40 60 80 100 120 140 3 6 9 1 2 1 5...

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