CH3se - The Cellular Level of Organization Chapter 3 Human...

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The Cellular Level of Organization Chapter 3 Human Anatomy and Physiology
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Cells Three Principal Parts Plasma Membrane Separates inside of cell from outside Cytoplasm All cellular content between plasma membrane and nucleus Cytosol Organelles Nucleus Large organelle that stores DNA
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Plasma Membrane Fluid Mosaic Model Fluid lipids with a mosaic of proteins
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Lipid Bilayer Phospholipids - 75% Hydrophilic head - phosphate group Hydrophobic tail - fatty acid Cholesterol - 20% Glycolipids - 5% Only in the membrane layer facing the extracellular fluid Selectively Permeable Nonpolar - permeable Polar, charged, large - impermeable Small, uncharged (ex. water) - slightly permeable
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Membrane Proteins Integral Extend into or through the bilayer Transmembrane - span the entire lipid bilayer Peripheral Loosely associated with polar heads Glycoproteins Forms glycocalyx - along with glycolipids Molecular signature
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Membrane Protein Functions Ion Channels Potassium ion channels, some are gated Transporters Glucose transporters Receptors Insulin receptor Enzymes Linker Cell Identity Marker MHC proteins Specificity
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CH3se - The Cellular Level of Organization Chapter 3 Human...

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