Week 7 Discussion Pathophysiological Mechanisms of Iron Deficiency Anemia Iron is an essential element needed for red blood cells and a is key component of oxygen transportation and storage of molecules (Ganz, 2003). Iron deficiency anemia (IDA) is the most common form of anemia and is associated with three stages of iron slowly being depleted. In the first stage, the body ’ s storage of iron used for red blood cell reproduction is used up. In the second stage, red blood cells are deficient in iron as they are transported to bone marrow. The third stage is when IDA manifestations usually appear due to the iron deficient red blood cells starting to enter venous circulation and cause a decrease in hemoglobin. With a decrease in he- moglobin, the body ’ s tissue does not receive the amount of oxygen it demands. Fatigue, weak- ness, shortness of breath and paleness clinical manifestations begin when iron intake remains de- pleted (Heuther & McCance, 2012). Chronic Inflammation Anemia Chronic Inflammation Anemia (IA) is caused by red blood cells not functioning normally, thus, altering the ability to absorb and use iron efficiently.
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- Spring '15
- Hemoglobin, Iron deficiency anemia, red blood cells