Lec08 01_28_08 Development

Lec08 01_28_08 Development - Lecture 8: Development January...

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Lecture 8: Development January 28, 2007 Cheung - Chapter 5
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Genes in pieces Gene contains exons and introns Both are transcribed into RNA Exons coding regions - retained Introns removed before translation - splicing Differential splicing – Different exons joined together More than one protein per gene.
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Why is there non-coding DNA? Occurs between and within ( introns) genes ~98% of genome Junk DNA? Functions: Regulatory Pseudogenes Transposons – Jumping genes Viral remnants
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More sources of individual variation Nature vs nurture Genes vs Environment Environmental effects Often subtle, but sometimes striking Some effects can be inherited
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Congenital (birth) defects 2-3% of births Genetic and environmental (intrauterine) Teratogenic effects Malformation of newborn Exposure to a teratogen Teratogens Lack of folic acid spina bifida Fetal alcohol syndrome
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This note was uploaded on 05/01/2008 for the course BSC 1005 taught by Professor Brist during the Spring '08 term at University of Central Florida.

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Lec08 01_28_08 Development - Lecture 8: Development January...

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