Genetics Final Study Guide

Genetics Final Study Guide - DNA Structure& Replication...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: DNA Structure & Replication- Pyrimidines Cytosine & Thymine →-Purines Adenine & Guanine →-Nucleotide chains= chemical bonds between sugars and & phosphate backbone-Hydrogen bonds connect bases-Antiparallelism-A&T= 2 bonds-C&G= 3 bonds-Negative phosphate groups attract to positive + “histones”-Chromatin coiled up DNA 30% DNA, histones, binding proteins & 10% RNA → → DNA Replication-semiconservative 2 double helices from one →-DNA unwinds, builds new nucleotide chain and anneals-Helicase- unwind and hold apart replicating DNA, also repairs errors in replicated DNA-primerase builds RNA primer at the start of each segment-DNA polymerase enzyme adds bases can only add to existing strand attaches to → → RNA primer-DNAp adds DNA to 3’ end replication only from 5’ to 3’ direction → →-2 nd strand replicates 3’ to 5’ DNA loops out and replication is discontinuous → → Okazaki fragments- 150 nucleotides sealed by ligase → From DNA to Protein-Translation DNA Protein folds and functions → → →- Replication Occurs only in S phase G1-S-G2-M → Transcription/ Translation Occurs all the time except during M RNA vs. DNA-differences-RNA= single stranded-RNA has Uracil for Thymine →-Ribose not Deoxyribose-DNA stores/ RNA controls mRNA- messanger- carries info that specifies a protein-specifies particular codon-cell type specific muscle cell for actin & myosin/ skin for keratin →-500- 4500 bases long-Start AUG Methionine → →-Stop UAG/ UGA/ UAA → rRNA- ribosomal- associate with certain proteins to form a ribosome, which structurally support and catalyze protein synthesis.-2 subunits separate in cytoplasm, join at site of init iation of protein synthesis-catalyze formation of peptide bonds (AA’s)-100-3,000 bases long t RNA- transfer- binds an m RNA anti- codon at one end and a specific am ino acid at the other and basically transports AA’s to a ribosome for protein synthesis. DNA Polymerase DNA Replication requires primer → → RNA Polymerase Transcription No primer attaches to template DNA → → → Replication Transcription Translation → → Transcription Factors- proteins which bind DNA at certain sequences, int iating t ranscription at specific sites...
View Full Document

This note was uploaded on 05/01/2008 for the course BIO 212 taught by Professor Frederick during the Fall '07 term at Wofford.

Page1 / 7

Genetics Final Study Guide - DNA Structure& Replication...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online