sample_midterm_1_2006

sample_midterm_1_2006 - YOUR NAME_ Student ID#_ MIDTERM 1...

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YOUR NAME__________________________ Student ID#_________________ 1 NPB 100 MIDTERM 1 SPRING, 2006 Your signature______________________ Please check this box if you do not want your exam returned in the bins in the hallway… Question Score Total 1 20 2 12 3 7 4 5 5 16 6 6 7 20 8 10 9 4 TOTAL 100
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YOUR NAME__________________________ Student ID#_________________ 2 Question 1. (20 points) You clone the cDNA for a novel ligand-gated channel that is selective for cations. You construct the following hydrophobicity plot based on the predicted amino acid sequence. Hydrophobicity index N Amino Acids COOH H 2 12 3 A. (2 points) Is the amino terminus of this molecule extracellular or intracellular? B. (2 points) Is the carboxy terminus of this molecule extracellular or intracellular? C. (2 points) How many membrane spanning regions are there? D. (3 points) Could the neurotransmitter binding site be located in region 2 of the molecule? E. (4 points) Why or why not? F. (3 points) Which region of the molecule (region 1, region 2, or region 3) is likely to have an excess of negatively charged amino acids?
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sample_midterm_1_2006 - YOUR NAME_ Student ID#_ MIDTERM 1...

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