Lecture Slides 1 - What is toxicology Toxicology I ENVH...

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Toxicology I ENVH 111 10/13/07 What is toxicology? “the science of poisons” or The study of adverse effects of chemicals on living organisms History of toxicology – Early evidence At the most basic level, classification of plants into harmful and safe Early humans used animal venoms and plant toxins in hunting, warfare and assassination Evidence of knowledge of digitalis (foxglove) and belladonna (deadly nightshade) dates back to 1500 B.C. Hippocrates (circa 400 B.C.) and other Greeks recorded types of poisons and their effects Ebers Papyrus – 1500 B.C. What is this? Caffeine The most widely used stimulant drug in the world Found commonly in: Coffee Tea Soda drinks
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History of caffeine 3000 B.C. - Tea discovered in China or introduced from India 850 AD – Coffee beans discovered in Ethiopia 1100 – First coffee trees cultivated. Beans used to make hot beverage 1450 – Japanese tea ceremony created and popularized 1475 – The world’s first coffee house opens in Constantinople 1610 – Dutch bring tea to Europe 1600s – Coffee is brought to Europe and spreads to Americas 1773 – Boston tea party 1971 – The original Starbucks opens in Pike Place Market History of Toxicology - Paracelsus “All substances are poisons; there is none which is not a poison. The right dose differentiates the poison from the remedy Lived 1493-1541 Huge leap forward in understanding! Modern Toxicology
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Lecture Slides 1 - What is toxicology Toxicology I ENVH...

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